
What Are Wrinkle Erasers (Neuromodulators)?
When we laugh, frown, raise our brows in surprise or furrow them in concentration, our facial muscles contract and the overlying skin creases. The creases are temporary when we are young. Our skin is healthy and supple, and the lines disappear when our muscles relax.
Over time, this changes. The quantity of collagen and elastin in our skin diminishes with age, and repeatedly moving our muscles in the same way can lead to wrinkles that remain visible even when our face is at rest.
Neuromodulators are natural, purified proteins that temporarily relax the muscles that cause expression lines. This allows the skin to smooth out so existing wrinkles are less visible, while also helping to prevent new lines from forming.
The key to achieving beautiful results with neuromodulators is the expertise and artistic vision of your injector. As a pioneer in functional aesthetic dermatology and the first physician ever to use Jeuveau (beyond clinical studies), Dr. Romine consistently leads the way in product knowledge and advanced injection techniques that maintain authentic expressions.
The Benefits of Wrinkle Erasers (Neuromodulators)
Neuromodulators are versatile treatments used to address both aesthetic and therapeutic concerns. Their many applications include:
- Prejuvenation to prevent forming lines
- Forehead smoothing
- Crow’s feet eraser
- Reducing "bunny lines" on the nose
- Eyebrow shaping
- Enhancing jawline shape
- Neck line eraser
- Improving lip lines and gummy smiles
- Lip flip to create the appearance of added volume
- Reducing chin dimpling
- Elevating downturned mouth corners
- Alleviating TMJ pain and teeth grinding
- Managing chronic migraines and tension headaches
- Treating hyperhidrosis (excessive sweating)
- Easing muscle tension in the shoulders and neck
The benefits may extend beyond the physical. Many patients report feeling more confident and refreshed after treatment, and research suggests that relaxing certain facial muscles associated with negative expressions has a positive impact on mood and stress levels.
During your consultation at BelleSante, we'll discuss which of these benefits align with your goals and create a plan to address your needs. The very happiest patients are those who return for their two-week follow-up after having our experts artistically work their magic with neuromodulators.

Types of Wrinkle Erasers (Neuromodulators)
Jeuveau™
Jeuveau™ – prabotulinumtoxinA-xvfs – is a newer, more precise neuromodulator that has a very similar molecular size of purified protein as Botox. Jeuveau is made through a proprietary unique Hi-Pure™ technology, leading to more precision clinically. In head-to-head studies, the injectors and patients preferred Jeuveau™ at all study points, including longevity of action, as well as natural look and feel.
Botox®
Botox® – onabotulinumtoxinA – is a highly purified, natural protein that is produced by the bacterium Clostridium botulinum. Botox® has been used successfully for decades for a variety of medical conditions and is an extremely safe way to reduce fine lines and wrinkles.
Dysport®
Dysport® – abobotulinumtoxinA – inhibits the release of the neurotransmitter acetylcholine and is a neuromuscular blocking agent that improves the appearance of fine lines and wrinkles. While similar to Botox® Cosmetic, some possible differences include time to effectiveness as some patients have reported seeing results quicker.
Your Treatment Experience at BelleSante
Your journey begins with a comprehensive consultation where we discuss your goals, assess your facial anatomy and observe your natural expressions to personalize your treatment plan.
On the day of your treatment, you'll be welcomed into our serene treatment space where your comfort is our priority. We begin by applying a topical numbing cream to ensure a comfortable experience. During this time, we'll explain our unique comfort measures, including our soothing "TAP-esthesia" technique, calming CBD drops, and guided breathing exercises that help reduce any anxiety you may feel.
Dr. Romine or Sara Romine, DNP, FNP-C, will guide you through a series of facial movements so they can identify the optimal injection points. Then, using ultra-fine needles, your expert injector will administer the treatment. Many patients are surprised by how quick and comfortable the process is, especially with our advanced comfort measures in place.

Recovery & Results
After your treatment, you can return to most daily activities immediately. We'll provide detailed aftercare instructions and schedule your follow-up appointment. While you can expect to start seeing the positive effects of treatment four to seven days after your appointment, sometimes as early as one to two days with Jeuveau, it is best to wait a full two weeks for final results. This subtle progression ensures natural-looking results that leave others noticing you look refreshed, but never obvious or overdone.
To maintain your results, we recommend scheduling treatments every three to four months as part of our BelleSante Skin Gym Exclusive treatment plan. Sticking to a consistent treatment schedule ensures your skin fitness is maintained and a return to your "baseline" is avoided. Additionally, regular treatments often lead to longer-lasting results, as the targeted muscles become naturally more relaxed over time.